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EF24

CAT: 0931-T27242-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T27242-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
342808-40-6
Target
Apoptosis, NF-κB, Caspase, p38 MAPK, ERK, MEK, ROS
Related Pathways
Proteases/Proteasome, Immunology/Inflammation, Apoptosis, NF-κB, MAPK
Purity
>99.99%
Bioactivity
EF24 (3,5-Bis[ (2-fluorophenyl) Methylene]-4-piperidinone) treatment increases the levels of activated caspase 3 and 9, and decreases the phosphorylated forms of MEK1 and ERK. EF24 shows potent anti-tumor activity in oral squamous cell carcinoma (OSCC) via deactivation of the MAPK/ERK signaling pathway.
Smiles
Fc1ccccc1\C=C1/CNC\C(=C/c2ccccc2F)C1=O
Molecular Formula
C19H15F2NO
Molecular Weight
311.33
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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BA3379-5EF24
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