DNS-8254

• Target:

  Others|||PDE

• Related Pathways:

  Others|||Metabolism

• Bioactivity:

  DNS-8254 is a potent and selective Phosphodiesterase 2 (PDE2) inhibitor for the treatment of Memory Disorders (hPDE2a IC50 = 8 nM, Rat Cl-int = 25.6 uL/min/mg) . DNS-8254 demonstrated significant memory enhancing effects in a rat model of novel object recognition.

• Smiles:

  CC=1C=C(N2C(N1)=NC=N2)[C@@H]3CN(C(=O)C4=CC(Br)=C(F)C=C4)CC(F)(F)C3

• Molecular Formula:

  C18H15BrF3N5O

• Molecular Weight:

  454.24

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1821107-98-5