AZ-PFKFB3-67

• Target:

  Others|||Bcl-2 Family|||Phosphatase|||Glucokinase

• Related Pathways:

  Metabolism|||Apoptosis|||Others

• Purity:

  0.9979

• Bioactivity:

  AZ-PFKFB3-67 is a potent and selective PFKFB3 kinase inhibitor with an IC50=11nM for PFKFB3, reduces MCL-1, and inhibits angiogenesis by decreasing lactic acid production and ATP levels in endothelial cells (ECs) in tube-forming assays, and has neuroprotective effects.

• Smiles:

  C (#N) C=1C=2C (N (CC=3C (C) =NOC3C) C1) =CC=C (OC4=CC=C (NC (=O) [C@@H]5CCCN5) C=C4) C2

• Molecular Formula:

  C26H25N5O3

• Molecular Weight:

  455.51

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1704741-11-6