AZ-PFKFB3-67

CAT: 0931-MF-0063831-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0063831-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1704741-11-6
Target
Others|||Bcl-2 Family|||Phosphatase|||Glucokinase
Related Pathways
Metabolism|||Apoptosis|||Others
Purity
0.9979
Bioactivity
AZ-PFKFB3-67 is a potent and selective PFKFB3 kinase inhibitor with an IC50=11nM for PFKFB3, reduces MCL-1, and inhibits angiogenesis by decreasing lactic acid production and ATP levels in endothelial cells (ECs) in tube-forming assays, and has neuroprotective effects.
Smiles
C(#N)C=1C=2C(N(CC=3C(C)=NOC3C)C1)=CC=C(OC4=CC=C(NC(=O)[C@@H]5CCCN5)C=C4)C2
Molecular Formula
C26H25N5O3
Molecular Weight
455.51
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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