Avadomide HCl

• Target :

  Others|||Molecular Glues|||NF-?B|||Apoptosis|||E1/E2/E3 Enzyme

• Related Pathways :

  Others|||NF-?B|||Ubiquitination|||PROTAC|||Apoptosis

• Bioactivity :

  Avadomide is an orally available pleiotropic pathway modulator with potential antineoplastic activity. CC-122 mimics an interferon response and has antitumor activity in DLBCL CC-122 binds Cereblon (CRBN) and promotes degradation of Ikaros and Aiolos in diffuse large B-cell lymphoma (DLBCL) and T cells in vitro, in vivo, and in patients, resulting in both cell autonomous as well as immunostimulatory effects.

• Smiles :

  Cl.O=C1NC(=O)C(N2C(=O)C3=C(N=C2C)C=CC=C3N)CC1

• Molecular Formula :

  C14H15ClN4O3

• Molecular Weight :

  322.75

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1398053-45-6