Auten-99 HBr

CAT: 0931-T26684-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0931-T26684-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1049780-58-6

Target

Others, Phosphatase

Related Pathways

Metabolism, Others

Purity

0.9917

Bioactivity

Auten-99 HBr (Auten-99) is a myotubularin phosphatase Jumpy inhibitor exerting potent neuroprotective effects. AUTEN-99 activates autophagy in cell cultures and animal models. AUTEN-99 appears to effectively penetrate through the blood-brain barrier, and impedes the progression of neurodegenerative symptoms in Drosophila models of Parkinson's and Huntington's diseases. Furthermore, the molecule increases the survival of isolated neurons under normal and oxidative stress-induced conditions. Thus, AUTEN-99 serves as a potent neuroprotective drug candidate for preventing and treating diverse neurodegenerative pathologies, and may promote healthy aging.

Smiles

Br.C1CN2C=C(SC2=N1)c1ccc(cc1)-c1ccccc1

Molecular Formula

C17H15BrN2S

Molecular Weight

359.28

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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M16499	AUTEN-99
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BUP07879-01	Auten-99 HBr
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Auten-99 HBr

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