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Apomine

CAT: 0931-T26644-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T26644-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
126411-13-0
Target
HMG-CoA Reductase, Apoptosis
Related Pathways
Metabolism, Apoptosis
Purity
>99.99%
Bioactivity
Apomine (SR-9223i), an inhibitor of HMG-CoA-reductase, promotes apoptosis of myeloma cells in vitro and has been implicated in the regulation of myeloma in vivo. Apomine accelerates the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase and stimulates low-density lipoprotein receptor activity. Apomine enhances the antitumor effect of lovastatin on myeloma cells by downregulating 3-hydroxy-3-methylglutaryl-CoA reductase.
Smiles
P(C(P(OC(C)C)(OC(C)C)=O)CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1)(OC(C)C)(OC(C)C)=O
Molecular Formula
C28H52O7P2
Molecular Weight
562.66
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
BA3290-10Apomine

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