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Aplaviroc hydrochloride

CAT: 0931-T26642-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T26642-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
461023-63-2
Target
Others, HIV Protease, CCR
Related Pathways
GPCR/G Protein, Immunology/Inflammation, Others, Microbiology/Virology, Proteases/Proteasome
Bioactivity
Aplaviroc is a human cellular CC chemokine receptor 5 (CCR5) entry inhibitor. Aplaviroc binds specifically to CCR5 and demonstrates potent anti-human immunodeficiency virus activity in vitro in the subnanomolar range. In vitro studies show that aplaviroc selectively inhibits the binding of a particular monoclonal antibody, 45531, to CCR5.
Smiles
Cl.CCCCN1C(=O)[C@H](NC(=O)C11CCN(Cc2ccc(Oc3ccc(cc3)C(O)=O)cc2)CC1)[C@H](O)C1CCCCC1
Molecular Formula
C33H44ClN3O6
Molecular Weight
614.17
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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