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AK301

CAT: 0931-T26585-03Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T26585-03Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
314022-97-4
Target
Apoptosis, Microtubule Associated
Related Pathways
Apoptosis, Cytoskeletal Signaling
Purity
0.9975
Bioactivity
AK301 is a potent and selective inhibitor of tubulin polymerization and an effective sensitizer of cancer cells to apoptotic ligands (EC50 < 200 nM) . Colon cancer cells arrested in mitosis with AK301 readily underwent a p53-dependent apoptosis following compound withdrawal and arrest release.
Smiles
C(=O)(C1=C(OCC)C=CC=C1)N2CCN(CC2)C3=CC(Cl)=CC=C3
Molecular Formula
C19H21ClN2O2
Molecular Weight
344.84
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

(4-(3-Chlorophenyl)piperazin-1-yl)(2-ethoxyphenyl)methanone

structure in first source

CAS Number314022-97-4
PubChem CID871395
IUPAC Name[4-(3-chlorophenyl)piperazin-1-yl]-(2-ethoxyphenyl)methanone
Molecular FormulaC19H21ClN2O2
Molecular Weight344.8
XLogP3.9
Topological Polar Surface Area32.8
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count3
Rotatable Bond Count4
Heavy Atom Count24
Formal Charge0
Complexity412
SMILES
CCOC1=CC=CC=C1C(=O)N2CCN(CC2)C3=CC(=CC=C3)Cl
InChI
InChI=1S/C19H21ClN2O2/c1-2-24-18-9-4-3-8-17(18)19(23)22-12-10-21(11-13-22)16-7-5-6-15(20)14-16/h3-9,14H,2,10-13H2,1H3
InChIKey
UTBDVNWZTNDVJV-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of (4-(3-Chlorophenyl)piperazin-1-yl)(2-ethoxyphenyl)methanone
CAS: 314022-97-4
CID: 871395
Formula: C19H21ClN2O2
MW: 344.8
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight344.8
XLogP33.9
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count3
Rotatable Bond Count4
Exact Mass344.1291556
Monoisotopic Mass344.1291556
Topological Polar Surface Area32.8 Ų
Heavy Atom Count24
Formal Charge0
Complexity412
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
BUP00993-01AK301

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