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AK301

CAT: 0931-T26585-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T26585-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
314022-97-4
Target
Apoptosis, Microtubule Associated
Related Pathways
Apoptosis, Cytoskeletal Signaling
Purity
0.9975
Bioactivity
AK301 is a potent and selective inhibitor of tubulin polymerization and an effective sensitizer of cancer cells to apoptotic ligands (EC50 < 200 nM) . Colon cancer cells arrested in mitosis with AK301 readily underwent a p53-dependent apoptosis following compound withdrawal and arrest release.
Smiles
C(=O)(C1=C(OCC)C=CC=C1)N2CCN(CC2)C3=CC(Cl)=CC=C3
Molecular Formula
C19H21ClN2O2
Molecular Weight
344.84
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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Alternative Products

CatalogName
BUP00993-01AK301

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