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Rebastinib

CAT: 0931-T2640-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T2640-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1020172-07-9
Target
Apoptosis, FLT, Bcr-Abl, Src
Related Pathways
Apoptosis, Angiogenesis, Tyrosine Kinase/Adaptors, Cytoskeletal Signaling
Purity
0.9984
Bioactivity
DCC-2036 (Rebastinib (DCC-2036) ) is a conformational control Bcr-Abl inhibitor for Abl1 (WT, IC50: 0.8 nM) and Abl1 (T315I, IC50: 4 nM), also inhibits LYN, SRC, HCK, FGR, FLT3, KDR, and Tie-2, and low activity to c-Kit. Rebastinib aimed at the Angiopoietin2-Tie2 pathway.
Smiles
CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3cc(nn3-c3ccc4ncccc4c3)C(C)(C)C)c(F)c2)ccn1
Molecular Formula
C30H28FN7O3
Molecular Weight
553.59
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
bs-83408C-01Rebastinib
B1404-50DCC-2036 (Rebastinib)
S2634-10mgRebastinib (DCC-2036)
MBS130966-01DCC-2036(Rebastinib)

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