Products for Research Use Only
RegisterLogin

GLX481304

CAT: 0804-HY-153977-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-153977-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
GLX481304 is a specific inhibitor of Nox-2 and -4, with IC50s of 1.25 μM. GLX481304 suppresses ROS production in isolated mouse cardiomyocytes and improves cardiomyocyte contractility. GLX481304 can be used for research of ischemic injury to the heart[1].
CAS Number
701224-63-7
UNSPSC
12352005
Target
NADPH Oxidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/glx481304.html
Purity
99.90
Solubility
DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CC1=CC(NC2=NC(N)=NC(CN3CCN(CC3)C4=CC(OC)=CC=C4)=N2)=CC=C1C
Molecular Formula
C23H29N7O
Molecular Weight
419.52
References & Citations
[1]Szekeres FLM, et al. A small molecule inhibitor of Nox2 and Nox4 improves contractile function after ischemia-reperfusion in the mouse heart. Sci Rep. 2021 Jun 7;11 (1) :11970.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-148936GLX481372
HY-153978GLX481369

Alternative Products

CatalogName
BA8041-5.1GLX481304

Popular Products