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Ppack trifluoroacetate

CAT: 0931-T25977-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-T25977-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
157379-44-7
Target
PAI-1, Others
Related Pathways
Others, Metabolism
Bioactivity
Ppack trifluoroacetate is a peptide derivative that irreversibly and specifically suppresses thrombin-mediated platelet activation by binding with high affinity to the active site of thrombin (Ki: 0.24 nM) . It has been utilized as an anticoagulant (100 μM) and to study thrombin-mediated fibrin deposition, angiogenesis, and proinflammatory processes.
Smiles
C(C(O)=O)(F)(F)F.C(N[C@@H](CCCNC(=N)N)C(CCl)=O)(=O)[C@H]1N(C([C@@H](CC2=CC=CC=C2)N)=O)CCC1
Molecular Formula
C23H32ClF3N6O5
Molecular Weight
564.99
Shipping Conditions
Ice Packs
Storage Temperature
-20°C