Brivanib (alaninate)

• Target:

  FGFR|||VEGFR|||Autophagy

• Related Pathways:

  Angiogenesis|||Autophagy|||Tyrosine Kinase/Adaptors

• Purity:

  0.9966

• Bioactivity:

  Brivanib Alaninate (BMS-582664) is the alaninate salt of a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic activity. Brivanib strongly binds to and inhibits VEGFR2, a tyrosine kinase receptor expressed almost exclusively on vascular endothelial cells; inhibition of VEGFR2 may result in inhibition of tumor angiogenesis, inhibition of tumor cell growth, and tumor regression.

• Smiles:

  C[C@H](COc1cn2ncnc(Oc3ccc4[nH]c(C)cc4c3F)c2c1C)OC(=O)[C@H](C)N

• Molecular Formula:

  C22H24FN5O4

• Molecular Weight:

  441.46

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  649735-63-7