Brivanib

• Target :

  Autophagy|||EGFR|||FGFR|||VEGFR

• Related Pathways :

  Tyrosine Kinase/Adaptors|||JAK/STAT signaling|||Autophagy|||Angiogenesis

• Purity :

  0.9887

• Bioactivity :

  Brivanib (BMS-540215) is an ATP-competitive inhibitor targeting VEGFR2 with an IC50 of 25 nM, exhibiting moderate potency against VEGFR-1 and FGFR-1, and over 240-fold selectivity against PDGFR-?. Phase 3.

• Smiles :

  C[C@@H](O)COc1cn2ncnc(Oc3ccc4[nH]c(C)cc4c3F)c2c1C

• Molecular Formula :

  C19H19FN4O3

• Molecular Weight :

  370.38

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  649735-46-6