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Pimozide

CAT: 0931-T2546-03Size: 1 mL - 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0931-T2546-03Size:1 mL - 10 mM (in DMSO)
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2062-78-4
Target
Parasite, Dopamine Receptor, STAT, Potassium Channel, Adrenergic Receptor
Related Pathways
JAK/STAT signaling, Neuroscience, Stem Cells, GPCR/G Protein, Microbiology/Virology, Membrane transporter/Ion channel
Purity
>99.99%
Bioactivity
Pimozide (R6238) is a diphenylbutylpiperidine derivative and a dopamine antagonist with the antipsychotic property. Pimozide selectively inhibits type 2 dopaminergic receptors in the central nervous system (CNS), thereby decreasing dopamine neurotransmission and reducing the occurrence of the motor and vocal tics and delusions of parasitosis. In addition, this agent antagonizes alpha-adrenergic and 5-HT2 receptors.
Smiles
Fc1ccc(cc1)C(CCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1ccc(F)cc1
Molecular Formula
C28H29F2N3O
Molecular Weight
461.55
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

Pimozide

Pimozide can cause developmental toxicity and female reproductive toxicity according to state or federal government labeling requirements.

CAS Number2062-78-4
PubChem CID16362
IUPAC Name3-[1-[4,4-bis(4-fluorophenyl)butyl]piperidin-4-yl]-1H-benzimidazol-2-one
Molecular FormulaC28H29F2N3O
Molecular Weight461.5
XLogP6.3
Topological Polar Surface Area35.6
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count7
Heavy Atom Count34
Formal Charge0
Complexity632
SMILES
C1CN(CCC1N2C3=CC=CC=C3NC2=O)CCCC(C4=CC=C(C=C4)F)C5=CC=C(C=C5)F
InChI
InChI=1S/C28H29F2N3O/c29-22-11-7-20(8-12-22)25(21-9-13-23(30)14-10-21)4-3-17-32-18-15-24(16-19-32)33-27-6-2-1-5-26(27)31-28(33)34/h1-2,5-14,24-25H,3-4,15-19H2,(H,31,34)
InChIKey
YVUQSNJEYSNKRX-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Pimozide
CAS: 2062-78-4
CID: 16362
Formula: C28H29F2N3O
MW: 461.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight461.5
XLogP36.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count7
Exact Mass461.22786888
Monoisotopic Mass461.22786888
Topological Polar Surface Area35.6 Ų
Heavy Atom Count34
Formal Charge0
Complexity632
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
HY-12987-01Pimozide
AR-P31675-01Pimozide Impurity 2 (N-Nitroso-Pimozide)
DXC19357-01Pimozide-d4

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