Osimertinib

• Target :

  EGFR

• Related Pathways :

  JAK/STAT signaling|||Tyrosine Kinase/Adaptors|||Angiogenesis

• Purity :

  >99.99%

• Bioactivity :

  Osimertinib (AZD-9291) is an EGFR third-generation inhibitor that inhibits the T790M resistance mutation produced by second-generation EGFR inhibitors with irreversible and oral activity. Osimertinib has antitumor activity for the treatment of EGFR-mutated non-small-cell lung cancer.

• Smiles :

  CN1C=C(C=2C1=CC=CC2)C3=NC(NC4=C(OC)C=C(N(CCN(C)C)C)C(NC(C=C)=O)=C4)=NC=C3

• Molecular Formula :

  C28H33N7O2

• Molecular Weight :

  499.61

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1421373-65-0