PKR-IN-C51

• Target :

  Serine Protease|||Serine/threonin kinase

• Related Pathways :

  Cell Cycle/Checkpoint|||Proteases/Proteasome|||Metabolism

• Purity :

  0.9894

• Bioactivity :

  PKR-IN-C51 is a dose-dependent and ATP-competitive protein kinase R (PKR) inhibitor that inhibits intracellular PKR activation and autophosphorylation in mouse macrophages with an IC50=9 ?M and Ki=3.4 ?M.Interferon-induced double-stranded RNA-activated protein kinase (PKR) is a widely expressed Ser/Thr kinase.

• Smiles :

  N1=CC=C(N=C1NCCC2=CNC=3C=CC=CC32)C=4C=5C=CC=CC5NC4C

• Molecular Formula :

  C23H21N5

• Molecular Weight :

  367.45

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1314594-23-4