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GW8510

CAT: 0931-T24125-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T24125-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
222036-17-1
Target
DNA/RNA Synthesis, CDK
Related Pathways
Cell Cycle/Checkpoint, DNA Damage/DNA Repair
Purity
0.9932
Bioactivity
GW8510 is a CDK2 (cell cycle protein-dependent kinase 2) inhibitor and RRM2 (Ribonucleotide Reductase Regulatory Subunit M2) inhibitor that affects DNA synthesis and antiproliferation in tumor cells. In mammalian aging models, GW851 improves cognition and prolongs lifespan, which may be related to the modulation of the expression of cell cycle-related protein p21 and CDK family genes, as well as the improvement of mitochondrial function.
Smiles
O=C1NC=2C=CC=3N=CSC3C2C1=CNC4=CC=C(C=C4)S(=O)(=O)NC5=NC=CC=C5
Molecular Formula
C21H15N5O3S2
Molecular Weight
449.51
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
BA3834-25GW8510

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