D-4418

CAT: 0931-T23936-02Size: 50 mgDry Ice: NoHazardous: No

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CAT#:0931-T23936-02Size:50 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

257892-34-5

Target

PDE, Others

Related Pathways

Others, Metabolism

Bioactivity

D-4418 is a PDE4 inhibitor. It has been in development as a novel anti-inflammatory therapy with asthma and chronic obstructive pulmonary disease being primary indications.

Smiles

C(NC1=C(Cl)N=CC(Cl)=C1)(=O)C=2C3=C(C(OC)=CC2)N=CC=C3

Molecular Formula

C16H11Cl2N3O2

Molecular Weight

348.18

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Chemical Information

5-Quinolinecarboxamide, N-(2,5-dichloro-3-pyridinyl)-8-methoxy-

CAS Number	257892-34-5
PubChem CID	9928260
IUPAC Name	N-(2,5-dichloro-3-pyridinyl)-8-methoxyquinoline-5-carboxamide
Molecular Formula	C16H11Cl2N3O2
Molecular Weight	348.2
XLogP	3.5
Topological Polar Surface Area	64.1
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	3
Heavy Atom Count	23
Formal Charge	0
Complexity	426

SMILES

COC1=C2C(=C(C=C1)C(=O)NC3=C(N=CC(=C3)Cl)Cl)C=CC=N2

InChI

InChI=1S/C16H11Cl2N3O2/c1-23-13-5-4-11(10-3-2-6-19-14(10)13)16(22)21-12-7-9(17)8-20-15(12)18/h2-8H,1H3,(H,21,22)

InChIKey

FSDOTMQXIKBFKJ-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 257892-34-5

CID: 9928260

Formula: C16H11Cl2N3O2

MW: 348.2

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	348.2
XLogP3	3.5
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	3
Exact Mass	347.0228320
Monoisotopic Mass	347.0228320
Topological Polar Surface Area	64.1 Å²
Heavy Atom Count	23
Formal Charge	0
Complexity	426
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

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Alternative Products

Catalog	Name
GTR19200418-01	D-4418
MPH02634	hsa-miR-4418 Primers
HY-R01017-01	Hsa-miR-4418 mimic
HY-RI01017A-01	Hsa-miR-4418 antagomir
HY-RI01017-01	Hsa-miR-4418 inhibitor
HY-R01017A-01	Hsa-miR-4418 agomir
MBS8294024-01	hsa-miR-4418 miRNA Inhibitor
MBS8311919-01	hsa-miR-4418 miRNA Agomir
MBS8317166-01	hsa-miR-4418 miRNA Antagomir
GTR19326994-01	Hsa-miR-4418 miRNA Mimic

D-4418

Chemical Information

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