BIRT-377

• Target :

  Integrin|||IL Receptor|||Interleukin

• Related Pathways :

  Immunology/Inflammation|||Cytoskeletal Signaling

• Purity :

  >99.99%

• Bioactivity :

  BIRT-377 is a negative allosteric and orally bioavailable inhibitor of ICAM-1 and LFA-1 (Ki = 25.8 nM) . BIRT-377 inhibits the production of IL-2 and can be used in studies about inflammatory and immune disorders.

• Smiles :

  CN1C(=O)N(C(=O)[C@@]1(C)Cc1ccc(Br)cc1)c1cc(Cl)cc(Cl)c1

• Molecular Formula :

  C18H15BrCl2N2O2

• Molecular Weight :

  442.13

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  213211-10-0