AKCI

CAT: 0931-T23693-02Size: 50 mgDry Ice: NoHazardous: No

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CAT#:0931-T23693-02Size:50 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

669750-88-3

Target

MDM-2/p53, Serine/threonin kinase, Others

Related Pathways

Cell Cycle/Checkpoint, Apoptosis, Others, Metabolism

Bioactivity

AKCI is a PPI inhibitor that acts by targeting the AURKC-IκBα interaction.

Smiles

CC1=NC(NC2=NCN(CCN3CCOCC3)CN2)=NC2=C(C)C=CC=C12

Molecular Formula

C19H27N7O

Molecular Weight

369.46

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Chemical Information

4,8-dimethyl-N-[3-(2-morpholin-4-ylethyl)-2,4-dihydro-1H-1,3,5-triazin-6-yl]quinazolin-2-amine

CAS Number	669750-88-3
PubChem CID	654580
IUPAC Name	4,8-dimethyl-N-[3-(2-morpholin-4-ylethyl)-2,4-dihydro-1H-1,3,5-triazin-6-yl]quinazolin-2-amine
Molecular Formula	C19H27N7O
Molecular Weight	369.5
XLogP	1.2
Topological Polar Surface Area	77.9
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	5
Heavy Atom Count	27
Formal Charge	0
Complexity	510

SMILES

CC1=C2C(=CC=C1)C(=NC(=N2)NC3=NCN(CN3)CCN4CCOCC4)C

InChI

InChI=1S/C19H27N7O/c1-14-4-3-5-16-15(2)22-19(23-17(14)16)24-18-20-12-26(13-21-18)7-6-25-8-10-27-11-9-25/h3-5H,6-13H2,1-2H3,(H2,20,21,22,23,24)

InChIKey

ZUHMBCQGKZNQCK-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 669750-88-3

CID: 654580

Formula: C19H27N7O

MW: 369.5

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	369.5
XLogP3	1.2
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	5
Exact Mass	369.22770851
Monoisotopic Mass	369.22770851
Topological Polar Surface Area	77.9 Å²
Heavy Atom Count	27
Formal Charge	0
Complexity	510
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Alternative Products

Catalog	Name
MBS5773460	AKCI

AKCI

Chemical Information

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