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Darglitazone

CAT: 0931-T22708-03Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T22708-03Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
141200-24-0
Target
PPAR
Related Pathways
Metabolism, DNA Damage/DNA Repair
Purity
0.9976
Bioactivity
Darglitazone (CP-86325) is a potent, selective agonist of PPAR-γ with antidiabetic actions. Darglitazone is effective in controlling blood glucose and lipid metabolism.
Smiles
C(CC(=O)C1=CC=C(CC2SC(=O)NC2=O)C=C1)C=3N=C(OC3C)C4=CC=CC=C4
Molecular Formula
C23H20N2O4S
Molecular Weight
420.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

Darglitazone

Darglitazone is an agent belonging to the glitazone class of antidiabetic agents with antihyperglycemic and anti-inflammatory activities. Darglitazone may be able to abrogate acute cerebral inflammatory responses via its suppression of proinflammatory gene expression.

CAS Number141200-24-0
PubChem CID60870
IUPAC Name5-[[4-[3-(5-methyl-2-phenyl-1,3-oxazol-4-yl)propanoyl]phenyl]methyl]-1,3-thiazolidine-2,4-dione
Molecular FormulaC23H20N2O4S
Molecular Weight420.5
XLogP4.1
Topological Polar Surface Area115
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count7
Heavy Atom Count30
Formal Charge0
Complexity643
SMILES
CC1=C(N=C(O1)C2=CC=CC=C2)CCC(=O)C3=CC=C(C=C3)CC4C(=O)NC(=O)S4
InChI
InChI=1S/C23H20N2O4S/c1-14-18(24-22(29-14)17-5-3-2-4-6-17)11-12-19(26)16-9-7-15(8-10-16)13-20-21(27)25-23(28)30-20/h2-10,20H,11-13H2,1H3,(H,25,27,28)
InChIKey
QQKNSPHAFATFNQ-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Darglitazone
CAS: 141200-24-0
CID: 60870
Formula: C23H20N2O4S
MW: 420.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight420.5
XLogP34.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count7
Exact Mass420.11437830
Monoisotopic Mass420.11437830
Topological Polar Surface Area115 Ų
Heavy Atom Count30
Formal Charge0
Complexity643
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
RFA20024-01Darglitazone
GTR19186022-01Darglitazone Sodium
HY-120160ADarglitazone (Sodium)

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