YKL-5-124

• Target:

  CDK

• Related Pathways:

  Cell Cycle/Checkpoint

• Purity:

  0.995

• Bioactivity:

  YKL-5-124, a potent, selective and covalent CDK7 inhibitor with an IC50 of 9.7 nM, 1300 nM and 3020 nM for CDK7/Mat1/CycH, CDK2 and CDK9 respectively, displays biochemical and cellular selectivity for CDK7 over CDK12/13.

• Smiles:

  CN (C) C[C@@H] (NC (=O) N1Cc2c (NC (=O) c3ccc (NC (=O) C=C) cc3) n[nH]c2C1 (C) C) c1ccccc1

• Molecular Formula:

  C28H33N7O3

• Molecular Weight:

  515.61

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1957203-01-8