YKL-05-099

CAT: 0931-MF-0013183-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0013183-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1936529-65-5
Target
SIK
Related Pathways
PI3K/Akt/mTOR signaling
Purity
0.9989
Bioactivity
YKL-05-099 is a salt-inducible kinase (SIK) inhibitor. It can inhibit the activity of SIK1 (IC50: 10 nM) and SIK3 (IC50: 30 nM), and has a slightly weaker inhibitory effect on SIK2 (IC50: 40 nM) . [1]
Smiles
COc1ccc(nc1)N1C(=O)N(Cc2cnc(Nc3ccc(cc3OC)C3CCN(C)CC3)nc12)c1c(C)cccc1Cl
Molecular Formula
C32H34ClN7O3
Molecular Weight
600.11
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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