MDR-652

CAT: 0931-T22360-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T22360-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1933528-96-1
Target
TRP/TRPV Channel
Related Pathways
Membrane transporter/Ion channel
Purity
0.9996
Bioactivity
MDR-652 is a highly specific and efficacious agonist of nonpungent transient receptor potential vanilloid 1 (TRPV1), with Ki values of 11.4 nM and 23.8 nM for hTRPV1 and rTRPV1, respectively, and EC50s of 5.05 nM and 93 nM for hTRPV1 and rTRPV1, respectively. MDR-652 is a potent topical analgesic.
Smiles
CC(C)(C)c1nc(c(CNC(=O)Nc2ccc(CO)c(F)c2)s1)-c1cccc(Cl)c1
Molecular Formula
C22H23ClFN3O2S
Molecular Weight
447.95
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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