Vacuolin-1

• Target:

  Autophagy|||PI3K

• Related Pathways:

  Autophagy|||PI3K/Akt/mTOR signaling

• Purity:

  0.9945

• Bioactivity:

  Vacuolin-1 is a cell-permeable inhibitor of Ca2+ dependent fusion of lysosomes to the cell membrane. It acts by inhibiting release of lysosomal content.vacuolin?1 is a potent and selective PIKfyve inhibitor and inhibits late?stage autophagy by impairing lysosomal maturation

• Smiles:

  Ic1cccc(\C=N\Nc2nc(nc(n2)N2CCOCC2)N(c2ccccc2)c2ccccc2)c1

• Molecular Formula:

  C26H24IN7O

• Molecular Weight:

  577.42

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  351986-85-1