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Fipronil

CAT: 0931-T2196-01Size: 1 mL - 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0931-T2196-01Size:1 mL - 10 mM (in DMSO)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
120068-37-3
Target
Apoptosis, Cytochromes P450, GABA Receptor, GluCls
Related Pathways
Microbiology/Virology, Apoptosis, Neuroscience, Metabolism, Membrane transporter/Ion channel
Purity
>99.99%
Bioactivity
Fipronil (Fluocyanobenpyrazole) is a broad-use insecticide that belongs to the phenylpyrazole chemical family. Fipronil is a broad-spectrum insecticide that disrupts the insect central nervous system by blocking GABA-gated chloride channels and glutamate-gated chloride (GluCl) channels, resulting in central nervous system toxicity. This causes hyperexcitation of contaminated insects' nerves and muscles. Specificity of fipronil on insects may come from a better efficacy on GABA receptor, but also because GluCl channels do not exist in mammals.
Smiles
NC=1N(N=C(C#N)C1S(C(F)(F)F)=O)C2=C(Cl)C=C(C(F)(F)F)C=C2Cl
Molecular Formula
C12H4Cl2F6N4OS
Molecular Weight
437.15
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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