CID 2745687

• Target :

  GPCR

• Related Pathways :

  Endocrinology/Hormones|||GPCR/G Protein

• Purity :

  0.9911

• Bioactivity :

  CID 2745687 is a moderately potent, concentration-dependent antagonist at human GPR35 with pIC50 = 6.70. CID 2745687 cannot effectively antagonize the agonist effects of either Zaprinast or Cromolyn disodium at rodent ortholog of GPR35 in vitro[1]. However, CID 2745687 can reverse lodoxamide-mediated anti-fibrotic effects in mice in vivo[2].

• Smiles :

  COC(=O)c1cnn(c1C=NNC(=S)NC(C)(C)C)-c1ccc(F)cc1F

• Molecular Formula :

  C17H19F2N5O2S

• Molecular Weight :

  395.43

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  264233-05-8