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CID 2745687

CAT: 0931-T21874-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T21874-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
264233-05-8
Target
GPCR
Related Pathways
Endocrinology/Hormones, GPCR/G Protein
Purity
0.9911
Bioactivity
CID 2745687 is a moderately potent, concentration-dependent antagonist at human GPR35 with pIC50 = 6.70. CID 2745687 cannot effectively antagonize the agonist effects of either Zaprinast or Cromolyn disodium at rodent ortholog of GPR35 in vitro[1]. However, CID 2745687 can reverse lodoxamide-mediated anti-fibrotic effects in mice in vivo[2].
Smiles
COC(=O)c1cnn(c1C=NNC(=S)NC(C)(C)C)-c1ccc(F)cc1F
Molecular Formula
C17H19F2N5O2S
Molecular Weight
395.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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