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A 841720

CAT: 0931-T21848-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T21848-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
869802-58-4
Target
GluR, Others
Related Pathways
Others, Neuroscience
Bioactivity
A-841720 is a potent, selective, and non-competitive antagonist of the mGlu1 receptor, exhibiting an IC 50 value of 10 nM specifically for the human mGlu1 receptor. It demonstrates a 34-fold greater selectivity for mGlu1 over mGlu5 (IC 50 of 342 nM), with negligible activity across a spectrum of other neurotransmitter receptors, ion channels, and transporters. Additionally, A-841720 possesses analgesic potential within a certain dose range [1] [2].
Smiles
N(C)(C)C1=C2C3=C(SC2=NC=C1)C(=O)N(C=N3)N4CCCCCC4
Molecular Formula
C17H21N5OS
Molecular Weight
343.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C