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PPM-18

CAT: 0931-T21693-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T21693-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
65240-86-0
Target
Others, NO Synthase
Related Pathways
Others, Immunology/Inflammation
Bioactivity
PPM-18 (NSC 73233) is a potent anti-inflammatory agent which inhibits nitric oxide synthase expression. PPM-18 is a potent inhibitor of iNOS expression by blocking the binding of NF-κB to promoter [1]. PPM-18 is an analog of Vitamin K remarkably suppressed the proliferation and induced apoptosis in bladder cancer cells [2].
Smiles
O=C1C=2C(C(=O)C=C1NC(=O)C3=CC=CC=C3)=CC=CC2
Molecular Formula
C17H11NO3
Molecular Weight
277.27
Shipping Conditions
Ice Packs
Storage Temperature
-20°C