Dihydrocapsaicin

CAT: 0931-T2163-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T2163-01Size:10 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

19408-84-5

Target

ROS, PI3K, Apoptosis, Akt, Bcl-2 Family, Caspase, Reactive Oxygen Species, TRP/TRPV Channel

Related Pathways

Cytoskeletal Signaling, Metabolism, Immunology/Inflammation, Apoptosis, NF-κB, Membrane transporter/Ion channel, Proteases/Proteasome, PI3K/Akt/mTOR signaling

Purity

0.9994

Bioactivity

Dihydrocapsaicin (CCRIS1589) is isolated from Capsicum fruit. Capsaicin is the primary active component of the heat and pain-eliciting lipid soluble fraction of the Capsicum pepper. Like capsaicin, dihydrocapsaicin is an irritant. Capsaicin is found in natural hot pepper extracts along with a number of impurities, including dihydrocapsaicin and several lesser impurities. Separation by HPLC is required in order to obtain pure dihydrocapsaicin. Dihydrocapsaicin represents about 10% of the compound present in commercial preparations purporting to be pure capsaicin, but it has about the same pungency as capsaicin. VR1 (vanilloid receptor 1) is a heat activated calcium ion channel which functions as a part of the normal nociceptive pain pathway. Capsaicin elicits a sensation of burning pain by activation of VR1 on small, non-myelinated polymodal C-type nociceptive nerve fibers. The potency of dihydrocapsaicin at VR1 appears equivalent to capsaicin. Antioxidant. Reduces oxidation of serum lipids. Mutagenic. Dihydrocapsaicin is an activator of VR1.

Smiles

C(NC(CCCCCCC(C)C)=O)C1=CC(OC)=C(O)C=C1

Molecular Formula

C18H29NO3

Molecular Weight

307.43

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Catalog	Name
300185	Dihydrocapsaicin
A14534-100	Dihydrocapsaicin 100mg
371367	Dihydrocapsaicin discontinued
HY-N0361S	Dihydrocapsaicin-d3
HY-N0361R-01	Dihydrocapsaicin (Standard)

Dihydrocapsaicin

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