NSC 66811

• Target :

  Mdm2|||MDM-2/p53

• Related Pathways :

  Apoptosis

• Purity :

  0.9694

• Bioactivity :

  NSC 66811is a novel inhibitor of the murine double minute 2 (MDM2) -p53 interaction. It binds to MDM2 with a Ki of 120 nM and activates p53 in cancer cells with a mechanism of action consistent with targeting the MDM2-p53 interaction.

• Smiles :

  Cc1ccc2ccc(C(Nc3ccccc3)c3ccccc3)c(O)c2n1

• Molecular Formula :

  C23H20N2O

• Molecular Weight :

  340.42

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  6964-62-1