Products for Research Use Only
RegisterLogin

WP1066

CAT: 0931-T2156-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T2156-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
857064-38-1
Target
STAT, JAK, Apoptosis
Related Pathways
Stem Cells, JAK/STAT signaling, Tyrosine Kinase/Adaptors, Angiogenesis, Apoptosis, Chromatin/Epigenetic
Purity
0.9973
Bioactivity
WP1066 is a inhibitor of JAK2 (IC50: 2.30 μM) and STAT3 (IC50: 2.43 μM) in HEL cells; shows activity to JAK2, STAT3/5, and ERK1/2, not JAK1 and JAK3. WP1066 has been used in trials studying the treatment of Melanoma, Brain Cancer, Solid Tumors, and Central Nervous System Neoplasms.
Smiles
C[C@H](NC(=O)C(=C\c1cccc(Br)n1)\C#N)c1ccccc1
Molecular Formula
C17H14BrN3O
Molecular Weight
356.22
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
A4140-10WP1066
A11795-100WP1066 100mg

Popular Products