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Methoxyamine HCl

CAT: 0931-T21320-01Size: 1 mL - 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0931-T21320-01Size:1 mL - 10 mM (in DMSO)
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
593-56-6
Target
Others, DNA/RNA Synthesis, Apoptosis
Related Pathways
Apoptosis, Others, DNA Damage/DNA Repair, Cell Cycle/Checkpoint
Purity
≥98%
Bioactivity
Methoxyamine HCl (Methoxyamine) covalently binds to apurinic/apyrimidinic (AP) DNA damage sites and inhibits base excision repair (BER), which may result in an increase in DNA strand breaks and apoptosis. Methoxyamine is an orally bioavailable small molecule inhibitor with potential adjuvant activity. This agent may potentiate the anti-tumor activity of alkylating agents.
Smiles
Cl.CON
Molecular Formula
CH6ClNO
Molecular Weight
83.51
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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