UNC 569 hydrochloride

CAT: 0931-T21302L-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T21302L-01Size:10 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Target

TAM Receptor, TAM Receptor

Related Pathways

Tyrosine Kinase/Adaptors

Purity

>99.99%

Bioactivity

UNC 569 hydrochloride is a reversible and ATP-competitive inhibitor of Mer with an IC50 of 2.9 nM and a Ki of 4.3 nM. UNC 569 hydrochloride inhibits Axl and Tyro3 with IC50s of 37 nM and 48 nM, respectively. UNC 569 hydrochloride can be used in studies about acute lymphoblastic leukemia and atypical teratoid/rhabdoid tumors.

Smiles

CCCCNC1=NC=C(C2=N1)C(C3=CC=C(F)C=C3)=NN2C[C@@H]4CC[C@@H](N)CC4.Cl

Molecular Formula

C22H30ClFN6

Molecular Weight

432.96

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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