Tacrolimus monohydrate

CAT: 0931-MF-0016911-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0016911-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
109581-93-3
Target
Autophagy|||Phosphatase|||FKBP|||Antibiotic|||Antibacterial
Related Pathways
Apoptosis|||Metabolism|||Immunology/Inflammation|||Autophagy|||Microbiology/Virology
Purity
0.992
Bioactivity
Tacrolimus monohydrate (LCP-Tacro) is a macrolide from the culture broth of a strain of Streptomyces tsukubaensis, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase, which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties. It prevents the activation of T-lymphocytes in response to antigenic or mitogenic stimulation in vitro and has strong immunosuppressive activity in vivo.
Smiles
O=C([C@@](CCCC1)([H])N1C(C([C@@]2(O)[C@H](C)C[C@H](OC)[C@@](O2)([H])[C@@H](OC)C[C@@H](C)C/C(C)=C/[C@H]3CC=C)=O)=O)O[C@H](/C(C)=C/[C@H]4C[C@@H](OC)[C@H](O)CC4)[C@H](C)[C@@H](O)CC3=O.O
Molecular Formula
C44H71NO13
Molecular Weight
822.05
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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