Adavosertib

• CAS Number :

  955365-80-7

• Target :

  Wee1

• Related Pathways :

  Cell Cycle/Checkpoint

• Purity :

  >99.99%

• Bioactivity :

  Adavosertib (MK-1775) is a small molecule inhibitor of the checkpoint kinase WEE1 (IC50: 5.2 nM) . It hinders the G2 DNA damage checkpoint.

• Smiles :

  C(C=C)N1N(C=2C(C1=O)=CN=C(NC3=CC=C(C=C3)N4CCN(C)CC4)N2)C=5N=C(C(C)(C)O)C=CC5

• Molecular Formula :

  C27H32N8O2

• Molecular Weight :

  500.6

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C