Estramustine

• Target:

  Microtubule Associated

• Related Pathways:

  Cytoskeletal Signaling

• Purity:

  0.9925

• Bioactivity:

  Estramustine (LEO-275) is a nitrogen mustard linked to estradiol, usually as phosphate. Estramustine has been used to treat prostatic neoplasms; also has radiation protective properties. Estramustine is selectively taken up by prostate cells and exerts antineoplastic effects by interfering with microtubule of dynamics and by reducing plasma levels of testosterone.

• Smiles:

  C[C@@]12[C@]([C@]3([C@@](C=4C(CC3)=CC(OC(N(CCCl)CCCl)=O)=CC4)(CC1)[H])[H])(CC[C@@H]2O)[H]

• Molecular Formula:

  C23H31Cl2NO3

• Molecular Weight:

  440.4

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2998-57-4