NNK

• Target :

  Lipoxygenase

• Related Pathways :

  Metabolism

• Purity :

  >99.99%

• Bioactivity :

  NNK is a nitrosated derivative of nicotine that activates the ERK1/2 and PKC? signaling pathways, induces Bcl2 phosphorylation at Ser70, and activates c-Myc at Thr58 and Ser62, thereby promoting the proliferation and survival of human lung cancer cells, and is commonly used to establish lung cancer mouse models.

• Smiles :

  CN(CCCC(=O)c1cccnc1)N=O

• Molecular Formula :

  C10H13N3O2

• Molecular Weight :

  207.23

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  64091-91-4