NNK

• Target:

  Lipoxygenase

• Related Pathways:

  Metabolism

• Purity:

  >99.99%

• Bioactivity:

  NNK is a nitrosated derivative of nicotine that activates the ERK1/2 and PKC? signaling pathways, induces Bcl2 phosphorylation at Ser70, and activates c-Myc at Thr58 and Ser62, thereby promoting the proliferation and survival of human lung cancer cells, and is commonly used to establish lung cancer mouse models.

• Smiles:

  CN (CCCC (=O) c1cccnc1) N=O

• Molecular Formula:

  C10H13N3O2

• Molecular Weight:

  207.23

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  64091-91-4