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NNK

CAT: 0931-T20533-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T20533-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
64091-91-4
Target
Lipoxygenase
Related Pathways
Metabolism
Purity
>99.99%
Bioactivity
NNK is a nitrosated derivative of nicotine that activates the ERK1/2 and PKCα signaling pathways, induces Bcl2 phosphorylation at Ser70, and activates c-Myc at Thr58 and Ser62, thereby promoting the proliferation and survival of human lung cancer cells, and is commonly used to establish lung cancer mouse models.
Smiles
CN(CCCC(=O)c1cccnc1)N=O
Molecular Formula
C10H13N3O2
Molecular Weight
207.23
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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