7-Hydroxymethotrexate

• Target:

  Drug Metabolite

• Related Pathways:

  Metabolism

• Purity:

  0.9972

• Bioactivity:

  7-Hydroxymethotrexate is the major metabolite of Methotrexate.Methotrexate is an inhibitor of folic acid, inhibiting dihydrofolate reductase, which prevents the conversion of folic acid to tetrahydrofolate, and inhibiting DNA synthesis.Methotrexate is also an inhibitor of metabolism.

• Smiles:

  NC1=C2C(NC(=O)C(CN(C)C3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)=N2)=NC(N)=N1

• Molecular Formula:

  C20H22N8O6

• Molecular Weight:

  470.44

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  5939-37-7