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7-Hydroxymethotrexate

CAT: 0931-T20339-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T20339-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
5939-37-7
Target
Drug Metabolite
Related Pathways
Metabolism
Purity
0.9972
Bioactivity
7-Hydroxymethotrexate is the major metabolite of Methotrexate.Methotrexate is an inhibitor of folic acid, inhibiting dihydrofolate reductase, which prevents the conversion of folic acid to tetrahydrofolate, and inhibiting DNA synthesis.Methotrexate is also an inhibitor of metabolism.
Smiles
NC1=C2C(NC(=O)C(CN(C)C3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)=N2)=NC(N)=N1
Molecular Formula
C20H22N8O6
Molecular Weight
470.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C