J-147

CAT: 0931-T1993-04Size: 25 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0931-T1993-04Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1146963-51-0

Target

Dopamine Receptor, Epigenetic Reader Domain, Monoamine Oxidase

Related Pathways

Neuroscience, Chromatin/Epigenetic, GPCR/G Protein

Purity

>99.99%

Bioactivity

J-147 is an experimental drug with reported effects against both Alzheimer's disease and ageing in mouse models of accelerated aging. It is a curcumin derivative and a potent neurogenic and neuroprotective drug candidate initially developed for the treatment of neurodegenerative conditions associated with aging that impacts many pathways implicated in the pathogenesis of diabetic neuropathy.

Smiles

COc1cccc(\C=N\N(C(=O)C(F)(F)F)c2ccc(C)cc2C)c1

Molecular Formula

C18H17F3N2O2

Molecular Weight

350.33

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Chemical Information

J147

J147 is an anilide.

CAS Number	1146963-51-0
PubChem CID	25229652
IUPAC Name	N-(2,4-dimethylphenyl)-2,2,2-trifluoro-N-[(E)-(3-methoxyphenyl)methylideneamino]acetamide
Molecular Formula	C18H17F3N2O2
Molecular Weight	350.3
XLogP	4.7
Topological Polar Surface Area	41.9
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	4
Heavy Atom Count	25
Formal Charge	0
Complexity	481

SMILES

CC1=CC(=C(C=C1)N(C(=O)C(F)(F)F)/N=C/C2=CC(=CC=C2)OC)C

InChI

InChI=1S/C18H17F3N2O2/c1-12-7-8-16(13(2)9-12)23(17(24)18(19,20)21)22-11-14-5-4-6-15(10-14)25-3/h4-11H,1-3H3/b22-11+

InChIKey

HYMZAYGFKNNHDN-SSDVNMTOSA-N

Chemical Structure

2D Structure

CAS: 1146963-51-0

CID: 25229652

Formula: C18H17F3N2O2

MW: 350.3

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	350.3
XLogP3	4.7
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	4
Exact Mass	350.12421228
Monoisotopic Mass	350.12421228
Topological Polar Surface Area	41.9 Å²
Heavy Atom Count	25
Formal Charge	0
Complexity	481
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	1
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

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T126552-01	Picrasidine J
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Alternative Products

Catalog	Name
TRC-J210300-100MG	J 147
BUP13417-01	J-147
TQA12174	AA 147
FH23825-01	JWH 147
9401-5	XL-147
cyt-1130-01	bFGF2 (147)
8077/2	MS 147
cyt-557-01	FGF2 (147)
FX137599-01	XL 147
HY-169568	EGFR-IN-147

J-147

Chemical Information

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