AZD4547

• Target :

  FGFR|||VEGFR

• Related Pathways :

  Angiogenesis|||Tyrosine Kinase/Adaptors

• Purity :

  0.9988

• Bioactivity :

  AZD4547 is an FGFR family inhibitor. AZD4547 selectively inhibits FGFR1 phosphorylation and suppresses cancer cell proliferation through inhibition of FGFR1 signaling, and is able to act on FGFR1 (IC50:0.2 nM), FGFR2 (IC50:2.5 nM), FGFR3 (IC50:1.8 nM) and FGFR4 (IC50:165 nM) . IC50:165 nM) .[2]

• Smiles :

  COc1cc(CCc2cc(NC(=O)c3ccc(cc3)N3C[C@H](C)N[C@H](C)C3)n[nH]2)cc(OC)c1

• Molecular Formula :

  C26H33N5O3

• Molecular Weight :

  463.57

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1035270-39-3