Sonidegib

• Target :

  Hedgehog/Smoothened|||Smo

• Related Pathways :

  Stem Cells|||GPCR/G Protein

• Purity :

  0.9997

• Bioactivity :

  Sonidegib (Erismodegib), a Smoothened (Smo) antagonist, inhibits Hedgehog (Hh) signaling with IC50 of 1.3 nM (mouse) and 2.5 nM (human), respectively.

• Smiles :

  CC1=C(C=CC=C1C(NC=2C=CC(=NC2)N3C[C@@H](C)O[C@@H](C)C3)=O)C4=CC=C(OC(F)(F)F)C=C4

• Molecular Formula :

  C26H26F3N3O3

• Molecular Weight :

  485.5

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  956697-53-3