Sonidegib

• Target:

  Hedgehog/Smoothened|||Smo

• Related Pathways:

  Stem Cells|||GPCR/G Protein

• Purity:

  0.9997

• Bioactivity:

  Sonidegib (Erismodegib), a Smoothened (Smo) antagonist, inhibits Hedgehog (Hh) signaling with IC50 of 1.3 nM (mouse) and 2.5 nM (human), respectively.

• Smiles:

  CC1=C(C=CC=C1C(NC=2C=CC(=NC2)N3C[C@@H](C)O[C@@H](C)C3)=O)C4=CC=C(OC(F)(F)F)C=C4

• Molecular Formula:

  C26H26F3N3O3

• Molecular Weight:

  485.5

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  956697-53-3