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Apitolisib

CAT: 0931-T1916-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T1916-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1032754-93-0
Target
PI3K, mTOR, Apoptosis
Related Pathways
Apoptosis, PI3K/Akt/mTOR signaling
Purity
0.9964
Bioactivity
Apitolisib (RG 7422), an effective, class I PI3K inhibitor for PI3Kα (IC50=5 nM), PI3Kβ (IC50=27 nM), PI3Kδ (IC50=7 nM), PI3Kγ (IC50=14 nM), is used in trials study of solid cancers, breast cancer, prostate cancer, renal cell carcinoma, and endometrial carcinoma, among others.
Smiles
C[C@H](O)C(=O)N1CCN(Cc2sc3c(nc(nc3c2C)-c2cnc(N)nc2)N2CCOCC2)CC1
Molecular Formula
C23H30N8O3S
Molecular Weight
498.6
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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