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Vc-MMAD

CAT: 0931-T18870-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T18870-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1401963-17-4
Target
Microtubule Associated, Drug-Linker Conjugates for ADC
Related Pathways
Cytoskeletal Signaling, Antibody-drug Conjugate/ADC Related
Purity
0.9885
Bioactivity
Vc-MMAD, a drug-linker conjugate for Antibody-Drug Conjugates (ADCs), combines the ADC linker Val-Cit (Valine-Citrulline) with the potent tubulin inhibitor MMAD. This compound leverages the targeting capability of ADCs to deliver the cytotoxic agent MMAD specifically to cancer cells, enhancing therapeutic efficacy while minimizing off-target effects.
Smiles
CCC(C)C(C(CC(=O)N1CCCC1C(OC)C(C)C(=O)NC(Cc1ccccc1)c1nccs1)OC)N(C)C(=O)C(NC(=O)C(C(C)C)N(C)C(=O)OCc1ccc(NC(=O)C(CCCNC(N)=O)NC(=O)C(NC(=O)CCCCCN2C(=O)C=CC2=O)C(C)C)cc1)C(C)C
Molecular Formula
C70H104N12O14S
Molecular Weight
1369.71
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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