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Mc-MMAD

CAT: 0931-T18311-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T18311-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1401963-15-2
Target
Microtubule Associated|||ADC Cytotoxin|||Drug-Linker Conjugates for ADC
Related Pathways
Antibody-drug Conjugate/ADC Related|||Cytoskeletal Signaling
Purity
0.9804
Bioactivity
Mc-MMAD is monomethyl auristatin D (MMAD) modified with the protective group maleimidocaproyl (Mc) . MMAD is a potent tubulin microtubule inhibitor that suppresses cancer cell proliferation and is commonly employed as a toxic payload in ADC synthesis.
Smiles
[H][C@]([C@@H](C)CC)([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)c1nccs1)OC)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)C(=O)CCCCCN1C(=O)C=CC1=O)C(C)C
Molecular Formula
C51H77N7O9S
Molecular Weight
964.26
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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