BX-912

• Target:

  PKA|||PDK|||Chk|||VEGFR|||Apoptosis|||CDK

• Related Pathways:

  Angiogenesis|||Apoptosis|||PI3K/Akt/mTOR signaling|||Tyrosine Kinase/Adaptors|||Cell Cycle/Checkpoint

• Purity:

  0.9934

• Bioactivity:

  BX-912 is a specific inhibitor of 3-Phosphoinositide-dependent Kinase-1 (PDK1, IC50: 12 nM) . The selectivity of BX-912 is more 10 fold than C-Kit, EGFR, PKA, PKC etc.

• Smiles:

  Brc1cnc(Nc2cccc(NC(=O)N3CCCC3)c2)nc1NCCc1cnc[nH]1

• Molecular Formula:

  C20H23BrN8O

• Molecular Weight:

  471.35

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  702674-56-4