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BX795

CAT: 0931-T1830-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T1830-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
702675-74-9
Target
C-Kit, PDK, Autophagy, IκB/IKK, Chk, CDK
Related Pathways
Autophagy, NF-κB, Cell Cycle/Checkpoint, PI3K/Akt/mTOR signaling, Tyrosine Kinase/Adaptors
Purity
0.9957
Bioactivity
BX795 is an effective and selective PDK1 inhibitor (IC50: 6 nM), and its selectivity is 140- and 1600-fold for PDK1 over PKA and PKC in cell-free assays, respectively. Meanwhile, the selectivity for PDK1 is 100-fold than GSK3β.
Smiles
Ic1cnc(Nc2cccc(NC(=O)N3CCCC3)c2)nc1NCCCNC(=O)c1cccs1
Molecular Formula
C23H26IN7O2S
Molecular Weight
591.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
A8222-SBX795

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