Clovamide

• Product Name Alternative:

  trans-Clovamide

• UNSPSC Description:

  Clovamide (trans-Clovamide), a natural phenolic compound, is a potent antioxidant. Clovamide is an excellent ROS and oxygen radical scavenger. Clovamide also has anti-inflammatory and neuroprotective effects[1][2]. Clovamide is an anti-microbial with activity against the human pathogens influenza A subtype H5N1, Trypanosoma evansi, and Heliobacter pylori[3].

• Target Antigen:

  Apoptosis; Bacterial; Influenza Virus; Reactive Oxygen Species

• Type:

  Natural Products

• Related Pathways:

  Anti-infection;Apoptosis;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB

• Field of Research:

  Inflammation/Immunology; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/clovamide.html

• Purity:

  98.09

• Solubility:

  DMSO : 125 mg/mL (ultrasonic;warming;heat to 60°C)

• Smiles:

  OC1=CC=C(C=C1O)/C=C/C(N[C@@H](CC2=CC=C(C(O)=C2)O)C(O)=O)=O

• Molecular Weight:

  359.33

• References & Citations:

  [1]Naike Ye, et al. Antioxidant studies by hydrodynamic voltammetry and DFT, quantitative analyses by HPLC-DAD of clovamide, a natural phenolic compound found in Theobroma Cacao L. beans. Food Chem. 2021 Mar 30;341(Pt 2):128260.|[2]S Fallarini, et al. Clovamide and rosmarinic acid induce neuroprotective effects in in vitro models of neuronal death. Br J Pharmacol. 2009 Jul;157(6):1072-84.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  53755-02-5