CL2A

• Target :

  ADC Linker

• Related Pathways :

  Antibody-drug Conjugate/ADC Related

• Bioactivity :

  CL2A is a pH-sensitive, cleavable PEG8- and triazole-containing PABC-peptide-mc linker, characterized by its ability to induce a bystander effect. It forms a disulfide bond with an antibody at a cysteine residue. Labetuzumab govitecan utilizes this linker for its drug conjugation[1].

• Smiles :

  C(C1CCC(C(NCC2=CN(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(COCC(N[C@H](C(NC3=CC=C(COC(O)=O)C=C3)=O)CCCCN)=O)=O)N=N2)=O)CC1)N4C(=O)C=CC4=O

• Molecular Formula :

  C51H79N9O18

• Molecular Weight :

  1106.22

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1846605-04-6